产品货号：
Z22163
中文名称：
NOX2/CYBB抗体
英文名称：
Anti-NOX2/CYBB Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-NOX2/CYBB Antibody |
| 指标别名 | CYBB;Cytochrome b 245 heavy chain;NOX2;p91 PHOX |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,IHC,IF |
| 基因名称 | CYBB |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | Rabbit polyclonal NOX2 antibody was raised against a 15 amino acid peptide near the amino terminus of human NOX2.The immunogen is located within amino acids 140 - 190 of NOX2. |
| 计算分子量 | 65kDa |
| 成分 | NOX2 antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | NOX2 antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | The NOX family of NAPDH oxidases is comprised of seven transmembrane proteins that oxidize intracellular NAPDH/NADH,causing electron transport across the membrane and the reduction of molecular oxygen to superoxide (1).NOX2,also known as cytochrome b beta (CYBB) is one of two proteins that make up Cytochrome b-245,thought to be a primary component of the microbicidal oxidase system of phagocytes.NOX2 deficiency is one of five described biochemical defects associated with chronic granulomatous disease (CGD) (2).Activation of the NOX2 enzyme complex in microglia is thought to be neurotoxic and may play a role in Alzheimer's and Parkinson's disease (3). |
| Uniprot ID | P04839 |
| 基因名全称 | Cytochrome b-245,beta polypeptide |
| 蛋白名全称 | Cytochrome b-245,beta polypeptide |
| 推荐稀释比 | NOX2 antibody can be used for detection of NOX2 by Western blot at 1 ～ 2μg/mL.Antibody can also be used for Immunohistochemistry starting at 2μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in rat samples;Immunohistochemistry in rat samples and Immunofluorescence in rat samples.All other applications and species not yet tested. |
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